In February 2019, DCLS screened 7,230 babies for 31 metabolic and hereditary disorders. One hundred and ninety-eight (198) babies were confirmed diagnosed with a critical disorder or with a carrier status during the month.
- Core Disorders
- Biotinidase deficiency, partial (BIO partial) 1
- Congenital adrenal hyperplasia, non-classical (CAH (NC)) 1
- Congenital adrenal hyperplasia, salt-wasting (CAH (SW)) 1
- Cystic fibrosis (CF) 1
- Hb S beta-thalassemia (Hb F,S,A) 1
- Hb SC-disease (Hb F,S,C) 1
- Hb SS-disease (sickle cell anemia) (Hb F,S) 3
- Hypothyroidism, primary congenital (CH) 1
- Low carnitine, transient (Low C0, transient) 1
- Medium-chain acyl-CoA dehydrogenase deficiency (MCAD) 4
- Secondary Disorders: disorders that can be detected in the differential diagnosis of a core
- CRMS (CF Related Metabolic Disorder) 1
- Cystic fibrosis carrier (CF carrier) 11
- FAB 14
- FACB 1
- FASB 2
- FASV 1
- Galactosemia carrier (GALT carrier) 9
- Hb C-carrier (Hb F,A,C) 32
- Hb D-carrier (Hb F,A,D) 1
- Hb E-carrier (Hb F,A,E) 3
- Hb S (sickle)-carrier (Hb F,A,S) 104
- Methylmalonic acidemia, deficiency of methylmalonyl-CoA mutase carrier (MUT carrier) 1
- Other Lymphopenia 1
- Thyroid-binding globulin deficiency (TBG) 1
- Tyrosinemia, transient (Tyr, transient) 1
Virginia's Newborn Screening Program is a partnership between DCLS and the Virginia Department of Health to screen each baby born in Virginia for certain rare yet serious metabolic and genetic disorders. Babies with these disorders look healthy at birth but can suffer devastating consequences, even death, if the disorder goes untreated.
Newborn screening, which Virginia first mandated in 1966, is required by law for all babies born in the Commonwealth. Five drops of blood taken from a baby's heel allows scientists to check for 31 disorders that range from the well-known Cystic Fibrosis to the relatively obscure Maple Syrup Urine Disease. The effects of these disorders and others can be treated and problems prevented if they are detected early.
DCLS receives about 120,000 samples and performs more than 4 million newborn screening tests a year. Operating seven days a week, including holidays, DCLS provides screening for all time-sensitive disorders everyday, to insure timely reporting and followup of results. To ensure the timely and safe arrival of the samples they handle, DCLS provides a courier service to pick up samples from hospitals and birthing centers throughout the state.
The Virginia Department of Health's newborn screening staff follows-up on abnormal test results for more than 20,000 infants each year, making sure that babies with the most critical test results are referred to the specialty care they need. DCLS can perform repeat tests on infants up to 6 months of age.
Newborn Screening Information
DCLS screens each baby born in Virginia for the following disorders:
Argininosuccinic Aciduria (ASA)
Beta-Ketothiolase Deficiency (BKT)
Biotinidase Deficiency (BIOT)
Carnitine Uptake Deficiency (CUD)
Congenital Adrenal Hyperplasia (CAH)
Cystic Fibrosis (CF)
Glutaric Acidemia Type I (GA-1)
Isovaleric Acidemia (IVA)
Long Chain Hydroxyacy-CoA Dehyrogenase Deficiency (LCHADD)
Maple Syrup Urine Disease (MSUD)
Medium Chain Acyl -CoA Dehydrogenase Deficiency (MCAD)
Methylmalonyl Adenosyl-Cobalamine Synthesis Defects (Cbl A& B)
Methylcrotonyl-CoA Carboxylase Deficiency (3MCC)
Methylmalonyl-CoA Mutase Deficiency (MUT)
Mucopolysaccharidosis Type 1 (MPS-1)
Multiple CoA Carboxylase Deficiency (MCD)
Propionic Acidemia (PROP)
Severe Combined Immunodeficiency (SCID)
Sickle Beta Thalassemia (Hb SBThal)
Sickle Cell Anemia (Hb SS)
Sickle Hemoglobin C Disease (Hb SC)
Tri-functional Protein Deficiency (TFP Deficiency)
Tyrosinemia I (TYR I)
Very Long Chain Acyl-CoA Dehydrogenase Deficiency (VLCADD)
3-Hydroxy-3Methylglutaryl-COA Lyase Deficiency (HMG)
See full disorder descriptions on the VDH NBS site using the following link:
By policy of the Division of Consolidated Laboratory Services:
- Virginia does not use retained blood spot samples for any purpose other than those for which it was originally intended
- DCLS does not retain samples indefinitely; those for infants with normal screen results are retained for six months, and samples that yielded abnormal results are retained for 10 years.
- Samples are retained in case it needs to be retested to verify or disprove the original results.
- All samples are held in a secure location, with access restricted to only authorized personnel until their destruction date.
- Samples are destroyed by microwave/incineration.
- Samples are never released without notarized, written parental consent.
- Samples are never released for or used for research purposes or for inclusion in other databases.
Newborn Screening Release: DCLS will provide copies of patient reports to citizens as required by The Centers for Medicare and Medicaid Services. Please print the following documents and submit the request to DCLS to receive a copy of your test results report.
PLEASE NOTE: Using the documentation provided below, copies of newborn screening reports can be requested for babies born in the Commonwealth of Virginia on or after March 1, 2001. No Newborn Screening records are available for babies born prior to that date.
Authorization and Consent for the Release of Medical Records - Instructions
Authorization and Consent for the Release of Medical Records
- Parent Brochure
- Parent Brochure - Spanish
- Virginia Laws and Regulations
- Virginia Department of Health Newborn Screening Services
- The Newborn Screening Education Program
- Centers for Disease Control and Prevention Newborn Screening
- The Newborn Screening Technical Assistance and Evaluation Program (NewSTEPs)
- New York/Mid-Atlantic Consortium for Genetic and Newborn Screening Services
- Baby's First Test
- Saving Babies Through Screening Foundation
Newborn Screening kits may only be ordered by hospitals, midwives, and physicians' offices. They may not be ordered by private citizens. Find more information on our Sample Kit Ordering page.
Prospective participants must go through an onboarding and validation process and obtain approval from DCLS prior to participating in Virginia’s NBS Data Exchange program. Find more information on our NBS Data Exchange page.
If you are an OZ Systems user and need to add a facility or practice to your drop down menu, please click here.