NEWBORN SCREENING PANEL

Laboratory: Newborn Screening

Test Description: The Virginia Newborn Screening Panel screens each baby born in the Commonwealth of Virginia for 33 genetic and metabolic disorders.

Order Approval Required? No

Specimen Type: Dried Bloodspot

Collection Container: Virginia Newborn Screening device with attached PE226 filter paper

Optimal Volume: Five (5) filled circles of blood, one drop per circle

Collection Guidelines:

• Newborn Screening Specimen Collection (7571)

• Instructions for Completing NBS Collection Device (14829)

• Hospitals, midwives, and physician offices may request collection devices by emailing DCLS_SSSKits@dgs.virginia.gov

Storage Instructions: After drying, collection device should be stored at 15-30°C from collection until shipment.

Transportation Instructions: For shipping carrier questions, please email DCLS_SSSKits@dgs.virginia.gov.

Test Methodology: Varied; including automated immunoassays, mass spectrometry, digital microfluidics, chromatography, and molecular testing.

Additional Information: Following testing, reports are made available to the submitter and provider listed on the collection card.

Causes for Rejection:

• Incorrect specimen type

• Improper collection

• Scratched or abraded cards

• Received wet

• Oversaturated

• Contamination

• Expired filter paper card

• Insufficient quantity of blood

• Specimen collected >6 months of age

• Specimen received at <-20°C or >30°C

• Specimen submitted with insufficient metadata

• Specimen received >10 days in transit